Everything about Fast Atom Bombardment totally explained
Fast atom bombardment (FAB) is an
ionization technique used in
mass spectrometry. The material to be analyzed is mixed with a non-volatile chemical protection environment called a
matrix and is bombarded under vacuum with a high energy (4000 to 10,000
electron volts) beam of atoms. The atoms are typically from an inert gas such as
argon or
xenon. Common matricies include
glycerol,
thioglycerol,
3-nitrobenzyl alcohol (3-NBA),
18-Crown-6 ether,
2-nitrophenyloctyl ether,
sulfolane,
diethanolamine, and
triethanolamine. This technique is similar to
secondary ion mass spectrometry and
plasma desorption mass spectrometry.
How it works
FAB is a relatively soft ionization technique and produces primarily intact protonated molecules denoted as [M+H]
+ and deprotonated molecules such as [M-H]
-. The nature of its ionization products places it close to
electrospray and
MALDI.
Further Information
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